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House dust mite asthma

Asthma severity among mite-sensitized individuals appears to be related to the degree of mite allergen exposure[1]. The documented increase in asthma has been almost entirely in perennial asthma and a large proportion of the cases are allergic to one of the common allergens found all year round in houses, i.e. house dust mites, cats, dogs or cockroaches. In population and case-control studies sensitization to one of these allergens is the strongest risk factor for asthma (adjusted odds ratios > or = 4).[2].

the majority of children admitted to hospital with exacerbations of asthma were exposed to house dust mite allergen and were house dust mite sensitive. Further the results suggest that continued exposure to higher concentrations of mite allergen may be associated with the risk of readmission.[3]. In addition to genetic factors, exposure in early childhood to house-dust mite allergens is an important determinant of the subsequent development of asthma.[4]


1. Sporik R, Hill DJ, Thompson PJ, Stewart GA, Carlin JB, Nolan TM, Kemp AS, Hosking CS. The Melbourne House Dust Mite Study: long-term efficacy of house dust mite reduction strategies. J Allergy Clin Immunol. 1998 Apr;101(4 Pt 1):451-6

2. Platts-Mills TA, Sporik RB, Chapman MD, Heymann PW

The role of domestic allergens. Ciba Found Symp. 1997;206:173-85; discussion 185-9.

3. Sporik R, Platts-Mills TA, Cogswell JJ. Exposure to house dust mite allergen of children admitted to hospital with asthma. Clin Exp Allergy. 1993 Sep;23(9):740-6.

4.Sporik R, Holgate ST, Platts-Mills TA, Cogswell JJ. Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood. A prospective study. N Engl J Med. 1990 Aug 23;323(8):502-7. Comment in:

N Engl J Med. 1991 Jan 31;324(5):337-8.

Γκέλης Ν.Δ. - Λεξικό Αλλεργίας - Εκδόσεις ΒΕΛΛΕΡOΦΟΝΤΗΣ - Κόρινθος 2013

Gelis Ν.D. - Dictionary of Allergies - VELLEROFONTIS Publications - Corinth 2013