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Λεξικό .. Food-dependent exercise-induced anaphylaxis

Food-dependent exercise-induced anaphylaxis

Anaphylaxis developed in some individuals when exercise is preceded by ingestion of a specific food, such as celery, lettuce, or shellfish [1, 2]. Food-dependent exercise-induced anaphylaxis is a unique form of food allergy. Recent studies indicate that gliadin is a major allergen in patients with wheat-dependent exercise-induced anaphylaxis (WDEIA)[3]. Objective or diagnostic proof of the condition is shown by a provocation test from ingestion of a food before or after exercise, according to clinical history, with assay of plasma histamine and spirometry or rhinomanometry.Usually the patients are atopic and can be demonstrated IgE antibodies to the responsible food or foods, by skin tests or RAST. Patients with WDEIA had higher levels of gliadin-specific IgE than patients without WDEIA (p = 0.003) [1].. Few of these patients need to avoid exercise altogether, but they should be advised to refrain from exercising for at least two hours after ingesting any food and to have with them a companion capable of administering adrenaline.


1. Sheffer, A.L.: Anaphylaxis. J. Allergy Clin. Immunol. 1986:75(2):227-33.2. 2. Sabbah, A.: L'anaphylaxie induite par l'exericse. Allergie et Immunologie: 1989:21:381-388.

3. Lee JY, Yoon S, Ye YM, Hur GY, Kim S, Park HS. Gliadin-specific IgE in wheat-dependent exercise-induced anaphylaxis. Allergy Asthma Proc. 2008 Nov-Dec;29(6):614-21

Γκέλης Ν.Δ. - Λεξικό Αλλεργίας - Εκδόσεις ΒΕΛΛΕΡOΦΟΝΤΗΣ - Κόρινθος 2013

Gelis Ν.D. - Dictionary of Allergies - VELLEROFONTIS Publications - Corinth 2013