Λεξικό .. Captopril

Captopril

An angiotensin-converting enzyme inhibitor (ACE-inhibitor). Captopril causes increases in the kinin levels in nasal secretions during the allergic response. If increased kinin levels persist or worsen with chronic therapy, it is possible that they could exacerbate allergic symptoms during repeated seasonal exposure. Patients treated with captopril or other ACE-inhibitor may demonstrate, as a side-effect, paroxysmal cough.

References

Proud D, Naclerio RM, Meyers DA, Kagey-Sobotka A, Lichtenstein LM, Valentine MD. Effects of a single-dose pretreatment with captopril on the immediate response to nasal challenge with allergen. Int Arch Allergy Appl Immunol. 1990;93(2-3):165-70.