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Λεξικό .. Canary grass, [Phalaris arundinacea]

Canary grass, [Phalaris arundinacea]

Canary grass, [Phalaris arundinacea. Φαλαρίς η καλαμοειδής]. A plant belonging to the family Poaceae which is originally a native of the Mediterranean region. The pollen of canary grass, which was introduced as a pasture grass from Europe to Australia, is a major allergen in the external environment of southern Australia. Suphioglu C et al (1993) identified by immunoblotting seventeen allergenic fractions of canary grass pollen, ranging in mol. mass from 14 to 100 kDa. They used IgE antibodies from sera of 24/30 grass-pollen-allergic subjects.

The highest frequency of IgE binding (77%) was to a major 34-kDa fraction (tentatively designated Pha a I). This protein has been partially purified and identified as a group I allergen by immunodepletion experiments, with partially purified Lol p I (from rye-grass pollen), atopic serum, and Lol p I-specific MAb. In addition, microsequencing of the N-terminus of Pha a I showed an amino acid sequence identical to Lol p I. In a separate study, IgE binding to Western blots of Pha a I, Lol p I, and Cyn d I was investigated in 24 sera and found to occur in 19/24, 18/24, and 9/24, respectively. IgE binding to all three major allergens, and to both Pha a I and Lol p I, occurred in 8/24 sera. Their findings suggest that while the N-terminal sequence of Pha a I is identical to Lol p I, there may be specific allergenic epitopes exclusive to this allergen that are important for allergenicity in southern Australia. Perennial See Phalaris arundinacea.

References

Suphioglu C, Singh MB, Simpson RJ, Ward LD, Knox RB. Identification of canary grass (Phalaris aquatica) pollen allergens by immunoblotting: IgE and IgG antibody-binding studies. Allergy. 1993 May;48(4):273-81.

Γκέλης Ν.Δ. - Λεξικό Αλλεργίας - Εκδόσεις ΒΕΛΛΕΡOΦΟΝΤΗΣ - Κόρινθος 2013

Gelis Ν.D. - Dictionary of Allergies - VELLEROFONTIS Publications - Corinth 2013