. Allergopedia

Λεξικό .. Atropine

Certain patients can respond well to anticholinergic drugs (e.g. atropine). Since anaphylaxis is associated with increased vagal afferent and efferent discharges and since cholinergic (muscarinic) drugs enhance mediator release, it is possible  that atropine may inhibit mediator release as well as inhibit cholinergically induced smooth muscle contraction. Atropine sulfate (AS) has been proven to be an effective bronchodilator when administered by aerosol route in a dose of 0.05 to 0.1 mg/kg in children.

Nevertheless, the rapid development of various effective inhaled â„¢-agonists during the past decade has diminished the use of AS in routine treatment of asthma. The simultaneous administration of atropine sulfate and isoetharine is safe and beneficial in some children with acute asthma.


Lew, D.B., et al: Combination of atropine and isoetharine aerosol therapy in pediatric acute asthma. ann. of Allergy 1990:64(Part II): 195.

Γκέλης Ν.Δ. - Λεξικό Αλλεργίας - Εκδόσεις ΒΕΛΛΕΡOΦΟΝΤΗΣ - Κόρινθος 2013

Gelis Ν.D. - Dictionary of Allergies - VELLEROFONTIS Publications - Corinth 2013