Λεξικό .. Anti-IgE and Asthma

Anti-IgE is an effective therapy for moderate to severe allergic asthma: it reduces frequency of exacerbations, improves symptom scores and reduces the requirements for steroid medication, very important especially for consideration of future treatment strategies for childhood asthma.

Similarly important, it is safe and well tolerated. Some of the improvements in symptom scores, exacerbation rates and lung function data during the course of the trials were also seen in the placebo-treated group, presumably demonstrating the benefits of continuous physician monitoring, but differences between the anti-IgE and the placebo-treated group reached significance for almost all important endpoints in favour for anti-IgE. Conclusively, the results show that anti-IgE is efficacious and safe for treatment of asthma.

References

Hamelmann, E., Rolinck-Werninghaus, C. & Wahn, U. From IgE to Anti-IgE: Where do we stand?.Allergy 2002: 57(11):983-994.