. Allergopedia

Dictionary of Allergies .. Vine pollen allergy

Vine pollen allergy, Aλλεργία στη γύρη της αμπέλου. Vine pollen could be the cause of pollinosis in exposed patients living in areas with a high density of vineyards shuch us Castilla-La Mancha, Spain an area with the highest density of vineyards in the world, 2 cases of Vitis vinifera pollen allergy have been previously reported. Brito FF, et al (2008), in order to determine the clinical relevance and biochemical characteristics of vine pollen in the Spanish province of Ciudad Real, designed a prospective study of patients treated in the allergy units from Puertollano and Ciudad Real for respiratory symptoms of 4 months' duration in the year 2000. Skin prick tests with a standard aeroallergen battery and V vinifera pollen extract were performed on all patients.

They also performed conjunctival and bronchial provocation tests and serum specific IgE and sodium dodecyl sulfate-polyacrylamide gel electrophoresis immunoblotting on the patients who tested positive for V vinifera pollen.

They included 200 patients, 98 sensitized to any pollen and 9 to V vinifera pollen. They found 8 of 9 positive conjunctival provocation test results and a positive bronchial provocation result to vine pollen in a vine grower. Serum specific IgE against V vinifera pollen was detected in 9 of 9 patients. Immunoblotting with V vinifera pollen extract showed IgE-binding bands at 45 and 67 kDa [1].

There is possibility a patient to be sensitive to to pollens from vine and also from grass, olive, and Chenopodiaceae plants and to develpe episodes of itching, maculopapular rash, and facial angioedema after eating grapes. Immunoblotting and inhibition assays may reveale cross-reactivity between the allergenic structures of vine pollen and grape fruit and also among botanically unrelated pollens[2].


1. Brito FF, Gimeno PM, Bartolomé B, Alonso AM, Lara P, Fernández JA, Martínez A. Vine pollen allergy in areas with a high density of vineyards. Ann Allergy Asthma Immunol. 2008 Jun;100(6):596-600.

2. Mur P, Feo Brito F, Bartolomé B, Galindo PA, Gómez E, Borja J, Alonso A. Simultaneous allergy to vine pollen and grape. J Investig Allergol Clin Immunol. 2006;16(4):271-3.

Γκέλης Ν.Δ. - Λεξικό Αλλεργίας - Εκδόσεις ΒΕΛΛΕΡOΦΟΝΤΗΣ - Κόρινθος 2013

Gelis Ν.D. - Dictionary of Allergies - VELLEROFONTIS Publications - Corinth 2013