. Allergopedia

Dictionary of Allergies .. Cross allergenicity

Cross allergenicity among pollen allergens is extensive and in general follows botanical relationships. Most of the common grasses fall into two broad cross-reacting groups, those associated with timothy and those associated with Bermuda Grass (in the USA). Cross reactivity is demonstrated in the ragweeds, where short, giant, western and false have the same major allergens, while southern and slender possesses fewer of these cross-reacting allergens. Cross allergenicity among the mold is unpredictable. Alternaria extensively cross reacts with Stemphyllium, Curvularia, Stachybotrys, and in some studies with Cladosporium, not with Aspergillus. Studies of Alternaria extracts have revealed spore specific allergens as well as allergens shared between spores and mycelia [1]..

Many patients have sensitivities to multiple species of storage and house dust mites. It is not clear if this is because patients have multiple sensitivities to species-specific mite allergens or if these mites share many cross-reacting allergens [2].


1. Burge, H.A.: Fungus allergens. Clin. Rev. Allergy 1985;3:319.Weber, R.W., Nelson, H.S.: Pollen allergens and their interrelationships. Clin. Rev. All. 1985;3:291.

2. Arlian LG, Morgan MS, Vyszenski-Moher DL, Sharra D. Cross-reactivity between storage and dust mites and between mites and shrimp. Exp Appl Acarol. 2009 Feb;47(2):159-72. Epub 2008 Oct 11.

Γκέλης Ν.Δ. - Λεξικό Αλλεργίας - Εκδόσεις ΒΕΛΛΕΡOΦΟΝΤΗΣ - Κόρινθος 2013

Gelis Ν.D. - Dictionary of Allergies - VELLEROFONTIS Publications - Corinth 2013