Dictionary of Allergies .. Beclomethasone dipropionate, διπροπιονική μπεκλομεθαζόνη

One of the shortest acting steroids, which is used only for topical administration as an inhaler or nasal spray. The precise mechanism of the drug's action in the lung is unknown. It controls hyperreactive airways and clears inflammation. Its inflammatory action directly suppresses the late phase reaction and effectively
inhibits the release of secondary mediators that perpetuate the vicious cycle of mast cell degranulation and airway inflammation. Dosage and administration: Adults and children 12 years of age and older: The usual recommended dosage is two inhalations (84 mcg) given three of four times a day. Alternatively, four inhalations (168mcg) given twice daily has been shown to be effective in some patients. In stable asthmatics, the control of asthma measured both symptomatically and by daily lung
function was independent of dosing schedule, but twice daily treatment may well lead to better compliance. (See Adrenal function, and beclomethazone dipropionate). Beclomethazone dipropionate is available in metered-dose
aerosol units which deliver 42 μg per actuation nasally (Vancenase, Beckons, Becotide) or orally (Vanceril, Beclovent).