Dictionary of Allergies .. Acrivastine

Acrivastine

An H1 antagonist (second generation H1-blocker) free of CNS sedation at doses recommended for the treatment of allergic rhinitis and urticaria. Because of the fast onset of action of acrivastine, treatment of life threatening anaphylactic reactions (e.g. after insect stings) with acrivastine should be considered.

Gex-Collet, CM et al; Inhibition of histamine or allergen induced wheals by a single dose of cetirizine or acrivastine. The Annual Meeting of the EAACI, Brussels, Belgium, July 3-7, 1999. Allergy, suppl. 52:54:56, 1999.

Simons FE. Comparative pharmacology of H1 antihistamines: clinical relevance. Am J Med. 2002 Dec 16;113 Suppl 9A:38S-46S.