Dictionary of Allergies .. Exercise-induced bronchoconstriction

Exercise-induced bronchoconstriction

Exercise-induced bronchoconstriction occurs in 80% to 90% of patients with Asthma [1]. EIB is especially limiting for children because it may interfere with activities important for physical and social development[2].Therefore one goal of asthma therapy is to minimize the impact of EIB on daily activities. Current recommendations for the treatment and prevention of EIB include the administration of short-acting β2-adrenergic agonist or cromolyn before exercise[3].  Kemp JP et al  reported protection against EIB by montelukast,  a leukotriene receptor antagonist in 6- to 14-year-old children with asthma.

References

1. Mellion MR, Kobayashi RM. Exerciseinduced asthma. Am Fam Physician 1992;45:2671-7.

2. Oseid S, Aas K. Exercise-induced asthma.Allergy 1978;33:227-8.

3. Global Initiative for Asthma. Global strategy for asthma management and prevention. NHLBI/WHO Workshop Report. Bethesda (MD): National Heart, Lung, and Blood Institute, National Institutes of Health; 1995. Publication number 95-3659.

4. Kemp JP, Dockhorn RJ, Shapiro GG, Nguyen HH, Reiss TF, Seidenberg BC, Knorr B. Montelukast once daily inhibits exercise-induced bronchoconstriction in 6- to 14-year-old children with asthma. J Pediatr. 1998 Sep;133(3):424-8