Dictionary of Allergies .. Aztreonam

Aztreonam

Aztreonam is a monocyclic β-lactam antibiotic which appears to lack cross-reactivity with other classes of β-lactams. In vitro studies have demonstrated  cross-allergenicity between aztreonam and ceftazidime, a third generation cephalosporin which is the only drug with the same side-chain. Patients with allergic reactions to aztreonam should  not be given ceftazidime, because the reactions are due to its side-chain.

References

Pérez Pimiento, A. Et al : Aztreonam and ceftazidime: evidence of in vivo cross-allergenicity. Allergy1998:53:624-625